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Evolution Nanomachines? You Must Be Kidding!

Posted by Roaring Lovely on October 12, 2015 at 6:00pm
THE PHYSICS OF FLAGELLUM MOTORA big problem with Dawrinism is that there is not always step by step simple roots to building a complex machine. Yes, there are varieties of motors. Some are more efficient than others. However, there is clearly the simplest motor possible. This simplest motor though is still a quantum jump from a no motor and it is still unbeleivable that such can occur by accident.The simples motor must have a rotor, a stator, an axle, power source and power drain. Four related acidents must happen! These requirements are dictated not by me but by 4 laws of physics: Newton's first and third law of motion and the first and the second law of thermodynamics.The flagellum motor is a version of Franklin's electrostatic motor. But the latter is powered by proton motive force. Like I said in the previous post, the later motor should start and stop at the will of the bacteria! This mean we cannot just make it the crude Franklin way that needs to be kicked to start and with no brakes. Such a motor will be useless to the bacteria!To achieve quick starts and stops, the center of the rotor must be made of a charged substance. However, the parts of surface proteins that are on the centre of the protein must be hydrophobic (they must repel water). The charged amino acids cannot be hydrophobic. This means that we must use as few charged amino acids as possible in the center. Priferably only one. There are only two charged amino acids. One is negative and the other is positive. We must not use a random mixture of both negative and positive ones! So we remain with only one option of amino acid: aspartate!Think carefully about this. A protein has to be folded over and over. Originaly, we are given just a giant chain of amino acids. How do we code the sequence in the DNA such that having beeng folded by the chaperone, the hydrophobic proteins lie near the center with aspartate at the center. If you were given such a chain, it will puzzle you!MAKING THE FLAGELLUMThe aim here is to show how realy absurd it is to think that a series of accidents can eventually make such things. Proteins are made when ribosome decodes the information in RNA. The information in RNA is in turn decoded from DNA by RNAp (RNA polymerase).RNAp reads the DNA by moving along it just like a zipper will move along a zip. However, if it merely moved anyhowly, it would never use the billions of codes in DNA to read zillions of proteins in an entire body. It would for instance go round and round rereading the same gene when duplicates of it is required. This mean something must control how RNAp moves along the DNA.The RNAp should be able to jump foward, backwards etc. It do so when a certain protein binds itself somewhere along the DNA. This protein then enables RNAp to begine from there otherwise RNAp cannot bind to the DNA. These 'address' proteins are ultimately generated due to the very job of RNAp itself! So in a roundabout way, RNAp simply controls itself! What it does determines what it will do. It is even perharps aware of itself!It seems to suggest that give genes that are aready existent, that are coding a part of a machine, an entirely different accident need not be done to recreate a perfect copy of that gene working in another system. For instance, protein A is made by fusing protein B and C. Protein D is made by fusing protein B and F. The gene for protein D need not to occur a new. Only F need to be inserted in the DNA. However, a new 'adress' protein is neaded. This is my point.At first glance, this seems to make evolution simpler. Infact, Dawrinist suggests such. Given that the components of the new comming system are already existent in other system we can simply integrate them in the new system. However, things are not any significantly simpler. A lot of unbeleivable acrobatics has to happen.Let us consider the 4 crucial parts of our motor. We wish to integrate their genes in a new system, call it z. Call the gene expression of the stator Y. Then y is already existent in system X. Normally, as RNAp reads through the DNA, just after it finish reading Y, the address protein, p is bound to a specific region that begines a gene that together with Y forms system X. But now another address protein, call it q must first bind to the region that will form part of Z. So a new gene expression exactly for q must accidentaly occur! This gene must be inserted before Y. But The gene for p was also before Y. To ensure that at times, RNAp simply goes straight to where p is bound so it may make system X as usual, another protein, call it unti-q must also accidentally be inserted before Y. Anti-q, binds to q to disable it. But at times, Anti-q is quickly secreted from the nuclear enabling the RNAp to go on to creat Z. So for every good use of an already existent gene, two symmetrical accidents must happen. In our case, 8 accidents must happen. In each accident, some thaousands of codes must be inserted in DNA just at the right places! In our case, it is only 4 parts. In the case of bacteria flagellum, there are over 40 parts! Btw in genetics, proteins such as p are called sigma factors and anti-p are called antisigma factors.TRANSPORT OF PROTEINSHow to transport the proteins to their destinies are entirely differen whole story on its own. Inside the cell are highly perfected roads and very efficient vehicles. These proteins walks to a fro along the roads. These roads are termed cytoskeleton. They are made of wonderfull proteins. Special transporters travel to special destinations.So in addition the gene that specifies the destination of the newly formed protein must also accidentaly occur. If there is no address or a wrong one is given, the entire job was useless. Such a gene will be quickly selected against!
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Comments

  • Roaring Lovely October 14, 2015 at 12:04pm
    I am writting a blog about the earth's core. Indead there seems to be crystals!
  • Feather Winger October 14, 2015 at 6:49am

    There is a giant crystal in the center of the earth.....this is what I´ve heard and what I connect with for grounding.   There could be a black hole type thing......guess we will see....

  • Roaring Lovely October 13, 2015 at 6:53pm
    The center of the earth too is worth thinking about.
  • Roaring Lovely October 13, 2015 at 6:52pm
    One remarkable thing in nature is a nuclear that more often acts as a control center of a system. It is recomendable to use one aspect of reality as an analogy to understand the other. So yes, the recurrent 'control centers' makes us wonder if the brain too has a nuclear.
  • Feather Winger October 13, 2015 at 6:03pm

    Since the universe is fractal, if we understand things on one level then we should understand all the rest......that is why I try to understand how my body works.

    One reason I was interested in the neuro-transmitters...oxytocin, serotonin, dopamine and all,  is because they come from the pituitary/pineal complex...which is also the control center of the brain.  I´m still exploring this....

  • Feather Winger October 13, 2015 at 5:48pm

    But there only needs to be one factor that is unknown and it throws the whole theory off.....The universe holds all the wild cards,,,and we have no idea what they are...

  • Roaring Lovely October 13, 2015 at 5:48pm
    Yea, exaustion is called 'opening black boxes'. A cell used to be largely treated as a black box. The box enclose an intellectual can of worms though. Now, biologists are more or less treating amino acids as black boxes. But what if we open the atom as well. Is it simple? Nope!

    The atom contain a masive neutron in the nuclear. It is recomendable to consider this neutral as a complex of everything it can decay into. We have electron-antielectron, z boson-anti-z boson etc. It can even posible encode an hypergene for making the DNA!!
  • Feather Winger October 13, 2015 at 5:45pm

    I´d say that infinite sounds like the right number....

  • Roaring Lovely October 13, 2015 at 5:33pm
    Yes, exactly. Considering ALL the factors is the gist of my point. Superficial gloss over explanations of natural phenomena is what I call it 'hand waving' There are many causal factors, possibly infinite.
  • Feather Winger October 13, 2015 at 4:07pm

    OK...I will check it...  When we consider evolution, or even the everyday life we need to see the gazillion ways that causes and conditions come together....how things are miraculously moved into place.  We can see the evolution of physical things and also the evolution of consciousness....how we meet the people we do and how information moves  through the world.....how certain life experiences lead one forward (often by appearing to send us backward).  It is all very complex this thing we call life and there are so many factors that are still unknown to us..

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