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  • I am reaching out to everyone for prayers for my husband. He has surgery coming up and has had toes removed from diabetes. He is currently going to the wound center for his wounds. They are going to put stents in for better blood flow to his feet next week.
  • Black Cumin (Nigella sativa) and Its Active Constituent, Thymoquinone: An Overview on the Analgesic and Anti-inflammatory Effects

      • PMID: 26366755


    For many centuries, seeds of Nigella sativa (black cumin), a dicotyledon of the Ranunculaceae family, have been used as a seasoning spice and food additive in the Middle East and Mediterranean areas. Traditionally, the plant is used for asthma, hypertension, diabetes, inflammation, cough, bronchitis, headache, eczema, fever, dizziness, and gastrointestinal disturbances. The literature regarding the biological activities of seeds of this plant is extensive, citing bronchodilative, anti-inflammatory, antinociceptive, antibacterial, hypotensive, hypolipidemic, cytotoxic, antidiabetic, and hepatoprotective effects. The active ingredients of N. sativa are mainly concentrated in the fixed or essential oil of seeds, which are responsible for most health benefits. This review will provide all updated reported activities of this plant with an emphasis on the antinociceptive and anti-inflammatory effects. Results of various studies have demonstrated that the oil, extracts, and their active ingredients, in particular, thymoquinone, possess antinociceptive and anti-inflammatory effects, supporting the common folk perception of N. Sativa as a potent analgesic and anti-inflammatory agent. Many protective properties are attributed to reproducible radical scavenging activity as well as an interaction with numerous molecular targets involved in inflammation, including proinflammatory enzymes and cytokines. However, there is a need for further investigations to find out the precise mechanisms responsible for the antinociceptive an


    Nigella sativa has attracted healers in ancient civilizations and researchers in recent times. Traditionally, it has been used in different forms to treat many diseases including asthma, hypertension, diabetes, inflammation, cough, bronchitis, headache, eczema, fever, dizziness and influenza. Experimentally, it has been demonstrated that N. sativa extracts and the main constituent of their volatile oil, thymoquinone, possess antioxidant, anti-inflammatory and hepatoprotective properties.

    In this review we aimed at summarizing the most recent investigations related to a few and most important effects of thymoquinone. It is concluded that thymoquinone has evidently proved its activity as hepatoprotective, anti-inflammatory, antioxidant, cytotoxic and anti-cancer chemical, with specific mechanisms of action, which provide support to consider this compound as an emerging drug. Further research is required to make thymoquinone a pharmaceutical preparation ready for clinical trials.

    Keywords: Anti-cancer, Anti-inflammatory, Antioxidant, Nigella sativa, Thymoquinone
  • Methods

    The plant attracts the interest of researchers all over the world, and a lot of investigations have reported its importance. Searching the database “PubMed” for the keyword, black cumin, gives 645 results, and searching for the keyword, Nigella sativa, gives more than 582 results. In preparing this review article we used the key words, Nigella sativa and thymoquinone, and the most recently published articles are cited in this review.

    Constituents of Nigella sativa

    N. sativa seeds contain fixed oil, proteins, alkaloids, saponins, and essential oil. The biological effects of N. sativa are attributed to the various characterized constituents (1). Thymoquinone (TQ), the most prominent constituent of N. sativa seeds essential oil has been intensive

    ly investigated, 406 research reports have been posted on the “PubMed” database about TQ since 1960. TQ has been ascribed many properties. In this review a selection of these properties will be discussed (Table 1).

  • I am also sharing with you about "black seed oil" a wonder oil in a soft gel that is natural and has Omega 3, 6, and 9 also has a natural drug called Thymoquinone: which is an emerging natural drug with a wide range of medical applications...The reason why I tell you about it is because a member of my family could not get better from her illness and her body system was shutting down...The doctors could not do much for her...She has been all her life with medications...She is here today and very healthy thanks to this oil which was told to us by a family friend that heard of her problem...It is good for the immune system and it is also anti-inflammatory... 1-800-241-9138...AMAZING HERBS '''If you decide to try it go slowly the first time to see how he reacts to it...It is natural, no chemicals or anything from the pharma industry...It is directly from nature...Give him one and wait a whole day or two to see if he gets any reactions...No reactions=more oil...then start giving him one a day, and pay attention how he is doing..

  • I have read your profile and I want to share what the higher beings of Love and Light have said about gluten and other components in food...{What is really harmful is the chemicals in your food...not so much the gluten which is a natural subtance) But all means keep avoiding gluten but also read the labels for chemicals in them...If possible buy ORGANIC foods...They are good for the eat lots of fruit and vegetables if possible organic...because non-organic are spread with chemicals too...Wash everything that is fresh...Blessings...

  • Mother Earth (Gaia) is following our steps when we walk barefoot...This practice connects us much more deeply to her and keep us rooted to her crystalline heart center...Blessings


  • Sending you Blessings of Peace, Love and Light...Have a beautiful day...

  • 8109418882?profile=original

  • I just came to you page for I saw your Avatar in the front page and I am glad I did...I am glad you are here...Blessings and feel free whenever possible to share with us and read the many blogs that will help you get inspired...for they are based on Truth and in Love...Blessings...


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Rudolph Wisconsin


June 18

About Yourself

I am a wife and mother. I take care of my husband that is on dialysis. He has been a diabetic since he was 7. My daughter has gluten allergies so I have tried to help them in living a happy life. I believe we are all children of God and I pray for peace and happiness for all.

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